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Myron R. Melamed

August 9, 1927 September 18, 2013
Myron R. Melamed
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Obituary for Myron R. Melamed

Father of Flow Cytometry Dies A co-inventor of a scientific device known as the Flow Cytometer has died. The invention spawned an entire field of clinical medicine and biomedical research known as Flow Cytometry. Today, the Flow Cytometer is ubiquitous throughout the worlds hospitals and research laboratories where it is utilized for applications ranging from monitoring transplant patients for signs of rejection to cutting edge research in drug discovery. It is an indispensible tool in the diagnosis and monitoring of Leukemia and Lymphoma. Myron Roy Melamed, MD, resident of Boca Raton, Florida, aged 86, died Wednesday September 186th after surviving 6 ½ years with pancreatic cancer. He was born in Cleveland, Ohio, to Jewish immigrant parents and graduated Phi Beta Kappa with a BS from Case Western Reserve at age 19. He earned his MD from the University of Cincinnati in 1950 where he was inducted into the Alpha Omega Alpha honor society. His residency and fellowship training included internal medicine, hematology, pathology, and histochemistry at the University of Cincinnati, Duke University Hospital, Mount Sinai in New York, and Hammersmith Hospital in London. He served overseas during the Korean Wwar as a Captain in the Army Medical Corps. Dr. Melamed was the Chairman of the Pathology Department at Memorial Sloan-Kettering Cancer Center from 1979 to 1989, and Cchairman of the Department of Pathology at Westchester Medical Center in Valhalla, NY from 1991 to 2007. He was a Professor of Pathology and Biology at Cornell University Medical College. His groundbreaking study, Natural History and Clinical Behavior of in situ Carcinoma of the Human Urinary Bladder, published in 1964, identified for the first time the source of invasive bladder cancer,opened new doors to the understanding of, and diagnosis and treatment of bladder cancer using then unprecedented techniques of cytologic analysis. The following year, he co-authored collaborated with Louis Kamentzky, a biomedical engineer at IBMs Watson Laboratory, on aa seminal paper entitled Spectrophotometer: New Instrument for Ultra-rapid Cell Analysis, which described thea device, now known as the Flow Cytometer., which has become an indispensible tool for research and clinical diagnosis. In 1990 he co-authored a study which, for the first time, confirmed that e association of second hand smoke can cause and lung cancer. Dr. Melamed received numerous awards and honors for his scientific research and teaching accomplishments including: the Papanicolaou Award of the American Society of Cytopathology, the Maurice Goldblatt Award of the International Society of Cytology, The Daniel Drake Award of the University of Cincinnati Medical School, and the Fred Stewart Award of the Memorial Sloan-Kettering Cancer Center for contributions in tumor pathology. He served on the Nobel Prize nominating committee for Medicine. He was a founding member and laterthen the president of the International Society for Analytical Cytology, served aspast president of the American Society of Cytology, and the New York Pathology Society, and served on the board of directors of the New York Transplant program. During his 63 years in the practice of medicine, he published more than 500 peer reviewed scientific papers and edited two text books. The most recent of these, the 5th edition of Koss Diagnosotic Cytology and its Histopathologic Bases is widely regarded as the most comprehensive and authoritative text on the subject. Dr. Melamed is survived by a younger sister, Rita Edlin, two sons, Daniel and Joseph, and two grandchildren, Alexander, and Caroline.

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